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Long-term follow-up after pediatric hematopoietic stem cell transplantation

2025/10/18 by Polliany Roberta Dorini Pelegrina, Roseane Vasconcelos Gouveia, Antônio Vaz de Macedo +8 · 1 voice
Medicine · #Acute Lymphoblastic Leukemia research #Childhood Cancer Survivors' Quality of Life #Hematopoietic Stem Cell Transplantation

paper · pdf · doi:10.46765/2675-374x.2025v6n1e286

openalex publication_date 2025/10/18 · openalex created_date 2025/10/19 · openalex updated_date 2026/07/22

Abstract

This article, part of the Pediatric Group consensus of the Brazilian Society of Bone Marrow Transplantation, addresses lifelong follow-up in pediatric hematopoietic stem cell transplant survivors. With the growing number of long-term survivors, specialized monitoring is essential, especially for high-risk groups such as infants, recipients of total body irradiation, and those with inherited bone marrow failure syndromes. The consensus outlines surveillance strategies for detecting and managing late complications, including chronic graft-versus-host disease and secondary effects. Multidisciplinary recommendations aim to optimize early intervention and quality of life, establishing a standardized follow-up framework for pediatric transplant care in Brazil.

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