2025/03/07 by Matic Lozinšek · 1 voice · 4 citations
Agricultural and Biological Sciences · Chemistry · Medicine · #Capsaicin #Chemistry #Crystallography #Free Radicals and Antioxidants #Phytochemicals and Antioxidant Activities #Ziziphus Jujuba Studies and Applications
paper · pdf · doi:10.1107/s2053229625001706
published in Acta Crystallographica Section C Structural Chemistry 81(4), 188-192
openalex publication_date 2025/03/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23
), or trans-8-methyl-N-vanillylnon-6-enamide, the natural product responsible for the spiciness of chilli peppers, was determined using low-temperature single-crystal X-ray diffraction. The reported crystal structure is in good agreement with previous determinations based on powder X-ray diffraction data. The localization and free refinement of all H atoms revealed that each capsaicin molecule is hydrogen bonded to four other molecules, with the O-H and N-H groups acting as hydrogen-bond donors, and the C=O group serving as a bifurcated hydrogen-bond acceptor.