2025/12/15 by Yusuke Yamada, Keisuke Sakurai, Akiya Fukuda +7 · 1 voice
Materials Science · Biochemistry, Genetics and Molecular Biology · #Enzyme Structure and Function #Advanced Electron Microscopy Techniques and Applications #Protein Structure and Dynamics
paper · doi:10.1107/s2059798325011234
openalex publication_date 2025/12/15 · openalex created_date 2025/12/21 · openalex updated_date 2026/07/23
Since the fiscal year 2022, `Support Program for Life Science and Drug Discovery Research (BINDS Phase II)', funded by the Japan Agency for Medical Research and Development (AMED), has been supporting structural analysis research in Japan, promoting the further development of various advanced structural analysis technologies. The BINDS project aims to offer more timely and cutting-edge support by establishing a new macromolecular crystallography endstation (MX-ES) at NanoTerasu, Japan's first fourth-generation synchrotron-radiation facility. MX-ES has been equipped with microbeam focusing optics and a state-of-the-art measurement system for fully automated, high-throughput data collection from cooled crystals. Commissioning and initial experiments have been completed. User operations are expected to begin in the second half of the fiscal year 2025.