2026/05/04 by Ana Fernandez-Agudo, Hannah Lester, Jose V. Tarazona +1 · 1 voice
Business, Management and Accounting · Medicine · #Biomedical Ethics and Regulation #Regulation and Compliance Studies #Science, Research, and Medicine
paper · doi:10.3389/ftox.2026.1829326
openalex publication_date 2026/05/04 · openalex created_date 2026/05/05 · openalex updated_date 2026/07/23
A gap between scientific research and regulatory frameworks continues to challenge the effective translation of science into policy and regulation. This commentary explores the disconnection between scientific research, regulatory agencies, and policymakers, highlighting the distinct yet interdependent roles they play. Researchers generate data, which is used by regulatory agencies for risk assessment, and these outcomes serve as the basis for policy development by policymakers. However, misalignments between these key stakeholders hinder effective integration, with consequences for advancing technological development. Additionally, it proposes a set of practical and strategic solutions that span academia, regulatory science, and policymaking to aid the effective integration of science into policy and regulation. Regulatory frameworks that encourage data harmonization, new options for validation, and accessibility are needed. Funding mechanisms that incentivize responsible and relevant research practices are also emphasized. Finally, the importance of open communication and targeted training for researchers and regulators to bridge knowledge gaps and build trust is also discussed. By addressing these issues, this manuscript aims to strengthen the synergy between scientific developments and regulation, advancing evidence-based policymaking. Enhancing robust, reliable and relevant science would improve regulatory decision-making processes, while also guiding researchers on responsible methodologies and setting standards for future research recommendations. The paper advocates for a collaborative approach to enhance the relevance and reliability of published research in guiding evidence-based regulation and policy.