2026/01/01 by Agus R. Poerwoprajitno, Alexander Malaj, O. Thompson Mefford +1 · 1 voice
Engineering · Environmental Science · Materials Science · #Coagulation and Flocculation Studies #Innovative Microfluidic and Catalytic Techniques Innovation #Nanoparticle-Based Drug Delivery
paper · doi:10.1039/d6nr00236f
openalex publication_date 2026/01/01 · openalex created_date 2026/05/15 · openalex updated_date 2026/07/22
Controlling the size of iron oxide nanoparticles while maintaining uniformity in flow-based synthesis systems has been a great challenge in nanoparticle synthesis. Using an extended LaMer mechanism, we improve both the size and shape uniformity as compared to a conventional flow synthesis. The key to this approach is the injection of additional Fe precursor during the flow reaction, providing extra precursor during the growth process leading to a size focusing step. This approach has also allowed for the systematic variation of the nanoparticle size produced in the flow reaction. These results represent a new synthetic concept for improving the size uniformity of iron oxide nanoparticles in flow-based synthesis and has potential for application across a wide range of nanoparticle systems.