A little nudge goes a long way: assessing the impact of a microbiology nudge comment on narrow-spectrum antibiotic use in uncomplicated Streptococcus pneumoniae bloodstream infections

2025/01/01 by Michael O. Akon, Rachel M. Kenney, Nathan Everson +5 · 1 voice
Medicine · Immunology and Microbiology · #Pneumonia and Respiratory Infections #Antibiotic Use and Resistance #Streptococcal Infections and Treatments

paper · pdf · doi:10.1017/ash.2025.10137

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/15

Abstract

Abstract Narrow-spectrum antibiotic prescribing (ampicillin IV or penicillin IV) was compared before and after implementing an interpretive microbiology comment for uncomplicated Streptococcus pneumoniae bloodstream infections. The postintervention group was associated with 4-fold increased odds of de-escalation to narrow-spectrum antibiotics (adjusted odds ratio, 4.66; 95% confidence interval, 1.97–11.00).

Discussions

• A clever microbiology nudge—a simple comment added to lab reports—led to a 4.6× increase in use of narrow-spectrum antibiotics for Streptococcus pneumoniae bloodstream infections. 🔗 doi.org/10.1017/ [bsky, 1 points, 0 comments]

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