Targeted delivery of berberine via ROS-sensitive polymersomes enhances its hepatoprotective activity in CCl 4 -intoxicated mice

2025/12/03 by Iva Suman, Damir Klepac, Martina Vragović +6 · 1 voice
Chemistry · Medicine · #Andrographolide Research and Applications #Asymmetric Hydrogenation and Catalysis #Berberine and alkaloids research

paper · pdf · doi:10.1039/d5na00706b

openalex created_date 2025/12/03 · openalex publication_date 2025/12/03 · openalex updated_date 2026/06/11

Abstract

Carbon tetrachloride (CCl 4 ) metabolism results in the production of free radicals and consequent liver tissue damage, making CCl 4 -induced liver injury an ideal model for studying drug delivery systems that respond to reactive oxygen species (ROS).

Citations

• Understanding MAPK Signaling Pathways in Apoptosis
• Toxicity of carbon tetrachloride, free radicals and role of antioxidants

Discussions

• #new_paper: argeted delivery of berberine via ROS-sensitive polymersomes enhances its hepatoprotective activity in CCl4-intoxicated mice @rsc.org: berberine, intoxicated mice doi.org/10.1039/D5NA... [bsky, 1 points, 0 comments]

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