Physical genomics: Why gene regulation is tug of war between polymer physics and biochemistry

2026/05/25 by Sarah Harris, Agnes Noy, Wilma K. Olson · 1 voice
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Advanced Physical and Chemical Molecular Interactions #DNA and Nucleic Acid Chemistry #Nanopore and Nanochannel Transport Studies

paper · doi:10.1016/j.sbi.2026.103285

openalex publication_date 2026/05/25 · crossref created 2026/05/25 · openalex created_date 2026/05/26 · crossref issued 2026/06/01 · crossref published 2026/06/01 · crossref published-print 2026/06/01 · crossref deposited 2026/07/07 · crossref indexed 2026/07/07 · openalex updated_date 2026/07/27

Citations

• Atomic Description of the Reciprocal Action between Supercoils and Melting Bubbles on Linear DNA
• Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA

Discussions

• Is gene regulation only dictated by biochemistry, or are we missing the bigger physical picture? 🧬✍️ Find our latest review article with Sarah A. Harris and Wilma K. Olson in Current Opinion in Struc [bsky, 1 points, 0 comments]