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Toward Multi-Modal Deep Learning for Pulmonary Disease Classification: A Texture-Based Machine Learning Pilot Study on Public Chest X-Ray Data

2026/07/29 by Yogisri Pujitha Chinthoti
Engineering · Computer Science · #eess.IV #cs.CV

paper · pdf

6 pages, 2 figures

arxiv created 2026/07/29 · arxiv updated 2026/07/31

Abstract

Automated classification of pulmonary disease from chest radiographs is a widely studied application of machine learning in medical imaging. This paper presents a pilot study evaluating classical texture- and gradient-based feature representations for distinguishing COVID-19 from other forms of pneumonia using the publicly available COVID-19 Image Data Collection (668 posteroanterior/anteroposterior radiographs from 408 patients). Using histogram of oriented gradients (HOG) and gray-level co-occurrence matrix (GLCM) texture descriptors with classical classifiers (logistic regression, random forest, and support vector machine), evaluated under patient-level 5-fold stratified cross-validation to prevent data leakage, we obtain a best mean accuracy of 75.4% and AUC of 0.755, modestly exceeding the 71.6% majority-class baseline. We report these results transparently, including their limitations, and use them to motivate and scope a proposed multi-modal deep learning architecture -- combining convolutional and transformer-based encoders across imaging modalities -- as a direction for future work requiring access to larger, multi-institutional, ethically sourced datasets.

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