2021/01/27 by Zhi Li, Rebecca Lamb, Mark C. Coles +3
Health Professions · Medicine · #Dermatology and Skin Diseases #Pressure Ulcer Prevention and Management #Wound Healing and Treatments
paper · pdf · doi:10.1111/imm.13312
openalex publication_date 2021/01/27 · crossref created 2021/01/27 · openalex created_date 2021/02/01 · crossref issued 2021/03/01 · crossref published 2021/03/01 · crossref published-online 2021/03/01 · crossref published-print 2021/05/01 · crossref deposited 2023/08/30 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/30
Whether resident and recruited myeloid cells may impair or aid healing of acute skin wounds remains a debated question. To begin to address this, we examined the importance of CD11c+ myeloid cells in the early activation of skin wound repair. We find that an absence of CD11c+ cells delays wound closure and epidermal proliferation, likely due to defects in the activation of the IL-23-IL-22 axis that is required for wound healing.