2020/09/02 by Jemima Ho, Giorgio Camilli, James S. Griffiths +3
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antifungal resistance and susceptibility #Gut microbiota and health #Psoriasis: Treatment and Pathogenesis
paper · pdf · doi:10.1111/imm.13255
openalex publication_date 2020/09/02 · crossref created 2020/09/02 · openalex created_date 2020/09/08 · crossref issued 2020/09/13 · crossref published 2020/09/13 · crossref published-online 2020/09/13 · crossref published-print 2021/01/01 · crossref deposited 2023/09/03 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31
As our understanding of mycology progresses, the impact of fungal microbes on human health has become increasingly evident. Candida albicans is a common commensal fungus that gives rise to local and systemic infections, particularly in immunocompromised patients where it can result in mortality. However, C. albicans has also been quietly linked with a variety of inflammatory disorders, to which it has traditionally been considered incidental; recent studies may now provide new aspects of these relationships for further consideration. This review provides a novel perspective on the impact of C. albicans and its peptide toxin, candidalysin, on human health, exploring their contributions to pathology within a variety of diseases.