2019/03/26 by Mohammed Abdul Waduud, Pratik Adusumilli, Michael Drozd +6
Medicine · #Frailty in Older Adults #Intensive Care Unit Cognitive Disorders #Nutrition and Health in Aging
paper · doi:10.1259/bjr.20180434
openalex publication_date 2019/03/26 · crossref created 2019/03/26 · crossref issued 2019/04/09 · crossref published 2019/04/09 · crossref published-online 2019/04/09 · crossref published-print 2019/05/01 · crossref deposited 2024/05/02 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31
Objective: We investigated whether total psoas muscle area (TPMA) was representative of the total psoas muscle volume (TPMV). Secondly, we assessed whether there was a relationship between the two commonly used single slice measurements of sarcopenia, TPMA and total abdominal muscle area (TAMA). Methods: Pre-operative CT imaging of 110 patients undergoing elective endovascular aneurysm repair were analyzed by two trained independent observers. TPMA was measured at individual vertebral levels between the second lumbar vertebrae and sacrum. TPMV was also estimated between the second lumbar vertebrae and sacrum. TAMA was measured at the third lumbar vertebrae (L3). Observer differences were assessed using Bland–Altman plots. Associations between the different measures were assessed using linear regression and Pearson’s correlation. Results: We found single slice measurements of the TPMA to be representative of the TPMV at individual levels between L2 to the sacrum. The strongest association was seen at L3 [adjusted regression coefficient 16.7, 95% confidence interval (12.1 to 21.4), p < 0.001]. There was no association between TPMA and TAMA [adjusted regression coefficient −0.7, 95% confidence interval (−4.1 to 2.8), p = 0.710]. Conclusion: We demonstrate that measurements of the TPMA between L2 to the sacrum are representative of the TPMV, with the greatest association at the third lumbar vertebrae. There was no association between the TPMA and TAMA. Advances in knowledge: We demonstrate that a single slice measurement of TPMA at L3 is representative of the muscle volume, contrary to previous criticism. Future sarcopenia studies can continue to measure TPMA which is representative of the TPMV.