Type IX class utilizing cell signals for organizing toxin–antitoxin systems

2026/03/26 by Eunsol Seo, Hyeon‐Ji Hwang, Hyeon-Ji Hwang +3 · 1 voice
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Cell death mechanisms and regulation #Immune Response and Inflammation #Toxin Mechanisms and Immunotoxins

paper · doi:10.1016/j.tim.2026.03.004

openalex publication_date 2026/03/26 · crossref created 2026/03/26 · openalex created_date 2026/03/27 · crossref issued 2026/07/01 · crossref published 2026/07/01 · crossref published-print 2026/07/01 · crossref deposited 2026/07/07 · crossref indexed 2026/07/07 · openalex updated_date 2026/07/10

Citations

• Structure and mechanism of antiphage retron Eco2
• Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes
• Direct activation of a bacterial innate immune system by a viral capsid protein

Discussions

• Congratulations on discovering yet another toxin/antitoxin system, the most-prevalent anti-phage system, known since 1996 (doi: 10.1128/jb.178.7.2044-2050.1996). Here, another type IX TAs (see doi.org [bsky, 1 points, 0 comments]