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Alcohol—a universal preventive agent? A critical analysis

2013/01/08 by Hans Olav Fekjær · 1 voice · 1 citation
Medicine · #Alcohol Consumption and Health Effects #Alcoholism and Thiamine Deficiency #Substance Abuse Treatment and Outcomes

paper · pdf · doi:10.1111/add.12104

openalex publication_date 2013/01/08 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/29

Abstract

BACKGROUND: In observational studies, moderate drinking is associated with a reduced risk of more than twenty different diseases and health problems. However, it would be premature to conclude that there is a causal relationship. METHOD: This paper critically reviews the evidence for such associations. FINDINGS: It was found that reasons for questioning the causal association of moderate drinking and a reduced health risk are: the lack of dose-response relationships; the characteristics and lifestyles of today's abstainers and moderate drinkers; the lack of plausible biological mechanisms; the problems in the classification of drinking groups, and; the general limitations of observational studies. CONCLUSIONS: The evidence for the harmful effects of alcohol is undoubtedly stronger than the evidence for beneficial effects.

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