2024/04/10 by Michael W. Cole · 1 voice · 1 citation
Neuroscience · #Functional Brain Connectivity Studies #Neural and Behavioral Psychology Studies #Neural dynamics and brain function
paper · doi:10.1016/j.cobeha.2024.101384
openalex publication_date 2024/04/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30
Our ability to overcome habitual responses in favor of goal-driven novel responses depends on frontoparietal cognitive control networks (CCNs). Recent and ongoing work is revealing the brain network and information processes that allow CCNs to generate cognitive flexibility. First, working memory processes necessary for flexible maintenance and manipulation of goal-relevant representations were recently found to depend on short-term network plasticity (in contrast to persistent activity) within CCN regions. Second, compositional (i.e. abstract and reusable) rule representations maintained within CCNs have been found to reroute network activity flows from stimulus to response, enabling flexible behavior. Together, these findings suggest cognitive flexibility is enhanced by CCN-coordinated network mechanisms, utilizing compositional reuse of neural representations and network flows to flexibly accomplish task goals.