High Time for Higher-Dose Rifampin

2025/01/03 by Nicole Maranchick, Charles A. Peloquin · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #Antibiotics Pharmacokinetics and Efficacy #Pneumonia and Respiratory Infections

paper · doi:10.1093/cid/ciaf005

openalex publication_date 2025/01/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

Nicole F Maranchick, Pharm.D, Charles Peloquin, Pharm.D., FCCP; High Time for Higher Dose Rifampin, Clinical Infectious Diseases, , ciaf005, https://doi.or

Discussions

• Should we double the starting dose of rifampicin (600mg/d➡️1200mg/d) for TB? ➡️Current dose is a minimally effective dose ➡️Rifamycins display concentration-dependent killing ➡️Meta-analyses showed d [bsky, 2 points, 1 comments]

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