Synthesis and functional screening of novel inhibitors targeting the HDAC6 zinc finger ubiquitin-binding domain

2024/12/27 by Silke Geurs, Eleni Staessens, Kato Bredael +16 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Chemical Synthesis and Analysis #Histone Deacetylase Inhibitors Research #Peptidase Inhibition and Analysis

paper · doi:10.1016/j.ejmech.2024.117208

openalex publication_date 2024/12/27 · openalex created_date 2024/12/27 · crossref created 2024/12/27 · crossref deposited 2025/02/24 · crossref issued 2025/03/01 · crossref published 2025/03/01 · crossref published-print 2025/03/01 · crossref indexed 2026/06/04 · openalex updated_date 2026/07/22

Citations

• OLEX2: a complete structure solution, refinement and analysis program
• Development and testing of a general amber force field
• Oxindole and its derivatives: A review on recent progress in biological activities

Discussions

• New Paper Alert! See our joint SynBioC – VIB-CMB work on #HDAC6 ubiquitin-binding domain inhibitors published in Eur. J. Med. Chem. doi.org/10.1016/j.ej... @elsevierconnect.bsky.social, with @rjhardin [bsky, 2 points, 0 comments]