Sum-frequency vibrational spectroscopy, a tutorial: Applications for the study of lipid membrane structure and dynamics

2024/05/01 by Joshua M. Taylor, John C. Conboy · 1 voice
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · Neuroscience · #Lipid Membrane Structure and Behavior #Spectroscopy and Quantum Chemical Studies #Photoreceptor and optogenetics research

paper · doi:10.1116/6.0003594

openalex publication_date 2024/05/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/26

Abstract

Planar supported lipid bilayers (PSLBs) are an ideal model for the study of lipid membrane structures and dynamics when using sum-frequency vibrational spectroscopy (SFVS). In this paper, we describe the construction of asymmetric PSLBs and the basic SFVS theory needed to understand and make measurements on these membranes. Several examples are presented, including the determination of phospholipid orientation and measuring phospholipid transmembrane translocation (flip-flop).

Citations

• Interspecimen Comparison of the Refractive Index of Fused Silica*,†

Discussions

• This #tutorial from authors at @utah.edu demonstrates how sum-frequency vibrational spectroscopy is used on planar supported lipid bilayers to study membrane structures & dynamics, like phospholipid o [bsky, 2 points, 0 comments]

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