Simultaneous conformity and non-conformity to Hammett’s linear free energy relationship (LFER): a rarity

2024/11/22 by Sanjeev Rachuru, V. Jagannadham, Adam A. Skelton · 1 voice
Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Physical and Chemical Molecular Interactions #Molecular spectroscopy and chirality #Protein Structure and Dynamics

paper · doi:10.1071/ch24110

openalex publication_date 2024/11/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/21

Abstract

Linear free energy relationships (LFERs) are an important topic in physical-organic chemistry. When one browses the literature, one encounters innumerable instances wherein the series in question conforms to LFER; one also encounters appreciable numbers of examples of non-conformity to LFER. It is extremely rare or maybe we are the first to report simultaneous conformity and non-conformity of Hammett’s relationship (LFER) in the same series, the para-substituted phenyl pentazoles. This rarity and a plausible reason are discussed.

Citations

• Definition of aromaticity basing on the harmonic oscillator model
• A survey of Hammett substituent constants and resonance and field parameters

Discussions

• Skelton and colleagues report simultaneous conformity and non-conformity of Hammett’s linear free energy relationships in the same system,  para-substituted phenyl pentazoles. This rarity and a plausi [bsky, 2 points, 0 comments]

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