Iron porphyrin-catalyzed bromination of unactivated C–H bonds: inhibition of oxygen rebound by redox-inactive metal ions

2025/01/01 by Yiran Xu, Peng Wu, Duanfeng Xie +4 · 1 voice
Chemistry · Medicine · #Metal-Catalyzed Oxygenation Mechanisms #Nitric Oxide and Endothelin Effects #Vanadium and Halogenation Chemistry

paper · pdf · doi:10.1039/d5qi00508f

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/21

Abstract

Biomimetic bromination of unactivated C–H bonds catalyzed by an iron porphyrin complex with LiBr was achieved. Introduction of Li + completely inhibited the oxygen-rebound pathway. A carbocation was proposed as the key intermediate for the reaction.

Discussions

• 🔒 In this #OpenAccess article, authors show that the redox-inactive metal ion acting as a #Lewis acid was capable of tuning the reactivity of high-valent #metal-oxo species from the #oxygen rebound t [bsky, 2 points, 0 comments]

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