2025/06/20 by Jennifer M. Farrell, Sam P. Brown · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Clostridium difficile and Clostridium perfringens research #Diabetes and associated disorders #Gut microbiota and health
paper · doi:10.1099/mic.0.001567
openalex publication_date 2025/06/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
In this primer, we will review the key distinctions between acute and chronic infections, between mono- and polymicrobial infections and how these distinctions work together to generate the growing crisis of chronic polymicrobial infections. Chronic (non-resolving) infections place a large and growing burden on human health, globally. Following an introduction to the basic properties of chronic polymicrobial infections, we will use an ecological and evolutionary perspective to help outline a research agenda for this field, flagging both challenges and opportunities for improved infection prevention, diagnosis and treatment.