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Synthetic biology for space exploration

2025/07/12 by Silvano Onofri, Ralf Moeller, Daniela Billi +18 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #Gene Regulatory Network Analysis #Space Science and Extraterrestrial Life #Spaceflight effects on biology

paper · pdf · doi:10.1038/s41526-025-00488-7

openalex publication_date 2025/07/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

Human space exploration faces different challenges. Topics like Bioregenerative Life Support Systems, In Situ Resource Utilization, and radiation protection, still require for more suitable solutions to be applied in long-term space exploration. Synthetic biology could be a powerful tool for enabling human exploration of space and planets. This paper explores key topics including resource utilization, life support systems, radiation protection, and human health, providing recommendations for short-, mid-, and long-term advancements in space exploration.

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