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Cryptococcus albidus (Naganishia albida) meningitis in a young patient with T-cell acute lymphoblastic leukaemia

2025/10/01 by Amber Prasad, Minakshi Singh, Priyal Anand · 1 voice
Medicine · #Antifungal resistance and susceptibility #Cytomegalovirus and herpesvirus research #Fungal Infections and Studies

paper · doi:10.1099/acmi.0.000920.v4

openalex publication_date 2025/10/01 · openalex created_date 2025/10/16 · openalex updated_date 2026/06/27

Abstract

Cryptococcus albidus , an emerging pathogen, poses diagnostic and therapeutic challenges, especially in immunocompromised patients. We report a case of C. albidus meningitis in a young T-cell acute lymphoblastic leukaemia patient, initially suspected to have Herpes Simplex Virus (HSV) encephalitis. CSF analysis confirmed C. albidus , leading to antifungal therapy with liposomal amphotericin B and flucytosine, resulting in clinical improvement. Elevated procalcitonin levels suggest a potential role in fungal infections. This case underscores the importance of early identification and appropriate treatment in C. albidus meningitis.

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