2025/08/28 by Emily A. Largent, Joshua D. Grill, Jason Karlawish +1 · 1 voice
Medicine · Health Professions · #Ethics in Clinical Research #Mental Health and Patient Involvement #Dementia and Cognitive Impairment Research
paper · pdf · doi:10.1002/bsa3.70035
openalex publication_date 2025/08/28 · openalex created_date 2025/08/30 · openalex updated_date 2026/07/26
Introduction: The steps of participant recruitment are described as a "funnel." In AD secondary prevention trials, the funnel typically yields an unrepresentative study population. Methods: A national survey of U.S. adults aged 65 and over assessed intention to enroll in a hypothetical secondary prevention trial. Among those intending to enroll, intention to ask someone to serve as their study partner was also measured. Results: In the full sample (n=603), intention to enroll - measured on a scale of 1 (very unlikely) to 5 (very likely) - was low (M: 2.37, SD: 1.31). Among those somewhat or very likely to enroll (24%, n=168), mean intention to ask a study partner was 3.45 out of 5 (SD 1.44). There were no significant differences between Black and White respondents. Discussion: Our results suggest underrepresentation of Black older adults in secondary prevention trials is not attributable to lower intention to participate or ask a study partner.