2025/05/28 by Lishu Yi, Hui Chen, Meixin Yang +5 · 1 voice
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Entomopathogenic Microorganisms in Pest Control #Mycotoxins in Agriculture and Food #Plant Pathogens and Fungal Diseases
paper · doi:10.1094/pdis-03-25-0680-re
openalex publication_date 2025/05/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Fusarium head blight (FHB), one of the most economically important diseases on wheat, is primarily managed through the application of chemical fungicides during the heading and flowering stages. To assess the long-term impact of different fungicidal mechanisms on the sensitivity of FHB pathogens, this study evaluated temporal changes in the sensitivity of Fusarium asiaticum to phenamacril (a novel cyanoacrylate fungicide) and tebuconazole (a sterol demethylation inhibitor fungicide). Sensitivity was determined by measuring mycelial growth inhibition in F. asiaticum field populations collected in 2008 (100 strains), 2021 (50 strains), and 2023 (50 strains) from Jiangsu and Anhui provinces of China, where FHB pressure and fungicide usage are high. A significant decline in F. asiaticum sensitivity to phenamacril over 15 years was observed, with EC 50 values nearly doubling between 2008 and 2023. In contrast, no notable change in sensitivity to tebuconazole was observed over the same period, indicating its stable inhibitory effect on F. asiaticum. These findings highlight the challenge of F. asiaticum adaptation to phenamacril, posing a significant concern for the long-term management of FHB in wheat cultivation.