2022/02/01 by Ana Luísa Nunes, Leonor Simoes, Carolina Figueiredo +3 · 1 voice
Medicine · #Autoimmune Bullous Skin Diseases #Drug-Induced Adverse Reactions #Peripheral Neuropathies and Disorders
paper · pdf · doi:10.14740/jmc3880
openalex publication_date 2022/02/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Infectious agents have been implicated in the pathogenesis of SLE. The emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a pro-inflammatory cytokine storm and has been linked to autoimmune phenomena, which can lead to the onset of autoimmune diseases. We report the case of a 70-year-old patient who developed a toxic epidermal necrolysis (TEN)-like subacute cutaneous lupus (SCL) as a severe presentation of SLE, 1 month after SARS-CoV-2 infection. After excluding other causes of SLE, treatment was initiated with a successful outcome.