2023/10/30 by Shukuo Zhao, Jinpu Zhou, Yongwen Zhang +1 · 1 voice
Engineering · Neuroscience · #Advanced Memory and Neural Computing #Neural dynamics and brain function #Neuroscience and Neural Engineering
paper · pdf · doi:10.1523/eneuro.0373-22.2023
openalex publication_date 2023/10/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Working memory (WM) can maintain sequential and concurrent information, and the load enhances the γ band oscillation during the delay period. To provide a unified account for these phenomena in working memory, we investigated a continuous network model consisting of pyramidal cells, high-threshold fast-spiking interneurons (FS), and low-threshold nonfast-spiking interneurons (nFS) for working memory of sequential and concurrent directional cues. Our model exhibits the γ (30-100 Hz) and β (10-30 Hz) band oscillation during the retention of both concurrent cues and sequential cues. We found that the β oscillation results from the interaction between pyramidal cells and nFS, whereas the γ oscillation emerges from the interaction between pyramidal cells and FS because of the strong excitation elicited by cue presentation, shedding light on the mechanism underlying the enhancement of γ power in many cognitive executions.