2021/10/28 by S. D. Shapoval, С. D. Shapoval, L. L. Vorontsova +2
Biochemistry, Genetics and Molecular Biology · Medicine · #Dermatology and Skin Diseases #Inflammasome and immune disorders #Urticaria and Related Conditions
paper · pdf · doi:10.26779/2522-1396.2021.5-6.53
crossref issued 2021/10/28 · crossref published 2021/10/28 · crossref published-online 2021/10/28 · openalex publication_date 2021/10/28 · crossref created 2021/12/10 · crossref deposited 2021/12/10 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31
Objective. To investigate the efficacy of immunomodulating and immunostimulating therapy in complex treatment of patients, suffering surgical forms of erysipelas.Materials and methods. Retrospectively and prospectively there were analyzed 284 patients’ hospital charts, who were treated stationary in Centre of Purulent-Septic Surgery of Zaporizhzhya Municipal Hospital №3 in 2016 - 2021 yrs. Results. In patients, suffering erythematous form of erysipelas, disorders in cellular and humoral chains of immunity were not revealed. The immune disorders formula in bullous form was following: CD3 + 1, CD4 + 1, CD8-1, CD16-2, CD22-1, what witnessed about misbalance of the immune system Degree I, of possibly compensatory character; in a phlegmonous one - CD3 + 1, CD4-1, CD8-1, CD16-2, CD22-1, witnessing actuality of the immune disorders of Degree І, while in the necrotic one - CD3-2, CD4-2, CD8-1, CD16-2, CD22-1, trusting presence of the immune disorders of Degree ІІI. Conclusion. Administration of erbisol-extra and laferon for destructive forms of erysipelas is pathogenetically substantiated and may be applied in complex treatment of the disease.