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The first case of genetically confirmed monozygotic twinning in the dog

2016/08/22 by Carolynne Joone, KGM De Cramer, J.O. Nöthling · 1 voice
Medicine · #Assisted Reproductive Technology and Twin Pregnancy #Prenatal Screening and Diagnostics #Reproductive Biology and Fertility

paper · doi:10.1111/rda.12746

openalex publication_date 2016/08/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Monozygotic twinning has not previously been genetically confirmed in the dog. This case report describes the finding of two viable male monozygotic foetuses within one placental site during caesarean section. Their umbilical cords attached to a single placenta. Genetic profiling using a total of 38 microsatellite markers, as well as amelogenin and SRY for sex determination, revealed identical DNA profiles, whether derived from blood or tissue (buccal swabs) samples. To the best of our knowledge, this is the first report of monozygotic twinning in the dog confirmed using DNA profiling.

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