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Streptococcus pyogenes Surveillance Through Surface Swab Samples to Track the Emergence of Streptococcal Toxic Shock Syndrome in Rural Japan

2025/05/13 by Dhammika Leshan Wannigama, Mohan Amarasiri, Phatthranit Phattharapornjaroen +31 · 2 voices
Biochemistry, Genetics and Molecular Biology · Medicine · #Bacterial Identification and Susceptibility Testing #Infective Endocarditis Diagnosis and Management #Streptococcal Infections and Treatments

paper · pdf · doi:10.1093/infdis/jiaf234

openalex created_date 2025/05/13 · openalex publication_date 2025/05/13 · openalex updated_date 2026/08/01

Abstract

Japan recently experienced a record surge in streptococcal toxic shock syndrome. Our environmental surveillance study reveals that Streptococcus pyogenes persists seasonally, peaking in autumn and winter in rural Japan. The dominant emm1 M1UK sublineage and csrS mutations heighten virulence, highlighting the urgent need for targeted surveillance and interventions.

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