Self-assembled monolayers: a journey from fundamental tools for understanding interfaces to commercial sensing technologies

2024/09/22 by Essam M. Dief, Richard D. Tilley, J. Justin Gooding · 1 voice
Biochemistry, Genetics and Molecular Biology · Engineering · #Advanced biosensing and bioanalysis techniques #Molecular Junctions and Nanostructures #Nanowire Synthesis and Applications

paper · pdf · doi:10.1071/ch24096

openalex publication_date 2024/09/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/07

Abstract

Self-assembled monolayers were first described in the 1980s and have now become ubiquitous in many interfacial technologies. In this account, we discuss different self-assembled monolayer systems, outlining their positives and negatives. We then overview other researchers’ work and our own group’s journey in using self-assembled monolayers to develop new concepts in sensing and addressing general challenges faced by many types of sensors. Finally, we reflect on some of the challenges monolayer chemistry needs to address to facilitate further use of this powerful surface chemistry in commercial devices.

Discussions

• This account by Gooding and colleagues outlines a variety of different self-assembled monolayer (SAM) systems and their application in sensing. Included is a reflection on challenges in facilitating f [bsky, 3 points, 0 comments]

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