2023/04/26 by Erik Jung, Karl Gademann
paper · doi:10.2533/chimia.2023.230
crossref issued 2023/04/26 · crossref published 2023/04/26 · crossref published-online 2023/04/26 · crossref created 2023/04/26 · crossref deposited 2023/04/26 · crossref indexed 2026/07/31
This review discusses small molecule antibiotics approved for clinical use in the time frame 2010-2022. This time span saw the approval of four synthetic antibiotics (bedaquiline, pretomanid, delafloxacin, tedizolid), nine natural product derivatives (ceftaroline fosamil, cefiderocol, plazomicin, omadacycline, eravacycline, sarecycline, lefamulin, dalbavancin, oritavancin), and one natural product (fidaxomicin).