2020/07/17 by Nihat Polat, Mustafa Oylumlu, Mehmet Ali Işık +6
Medicine · #Acute Myocardial Infarction Research #Blood Pressure and Hypertension Studies #Cardiovascular Function and Risk Factors
paper · doi:10.1177/0003319720941747
crossref issued 2020/07/17 · crossref published 2020/07/17 · crossref published-online 2020/07/17 · openalex publication_date 2020/07/17 · crossref created 2020/07/17 · crossref published-print 2020/11/01 · openalex created_date 2025/10/10 · crossref deposited 2026/04/28 · openalex updated_date 2026/07/28 · crossref indexed 2026/07/28
In patients with unstable angina pectoris (UAP) or non-ST elevation myocardial infarction (NSTEMI), long-term mortality remains high despite improvements in the diagnosis and treatment. In this study, we investigated whether serum albumin level is a useful predictor of long-term mortality in patients with UAP/NSTEMI. Consecutive patients (n = 403) who were hospitalized with a diagnosis of UAP/NSTEMI were included in the study. Patients were divided into 2 groups based on the presence of hypoalbuminemia and the relationship between hypoalbuminemia and mortality was analyzed. Hypoalbuminemia was detected in 34% of the patients. The median follow-up period was 35 months (up to 45 months). Long-term mortality rate was 32% in the hypoalbuminemia group and 8.6% in the group with normal serum albumin levels ( P < .001). On multivariate analysis, hypoalbuminemia, decreased left ventricular ejection fraction, and increased age were found to be independent predictors of mortality ( P < .05). The cutoff value of 3.10 g/dL for serum albumin predicted mortality with a sensitivity of 74% and specificity of 67% (receiver-operating characteristic area under curve: 0.753, 95% CI: 0.685-0.822). All-cause long-term mortality rates were significantly increased in patients with hypoalbuminemia. On-admission albumin level was an independent predictor of mortality in patients with UAP/NSTEMI.