Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition

2022/08/01 by Yung Su Kim, Rui Fan, Sanne C. Lith +11 · 1 voice · 6 citations
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Pluripotent Stem Cells Research #Renal and related cancers

paper · doi:10.1016/j.devcel.2022.07.011

crossref issued 2022/08/01 · crossref published 2022/08/01 · crossref published-print 2022/08/01 · openalex publication_date 2022/08/01 · crossref created 2022/08/22 · openalex created_date 2025/10/10 · crossref deposited 2026/05/12 · crossref indexed 2026/05/12 · openalex updated_date 2026/06/19

Citations

• KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell–cell junctions
• Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells
• Tricellular junctions: how to build junctions at the TRICkiest points of epithelial cells

Cited by

• Three-dimensional rosettes in epithelial formation
• Cell shape dynamics during mouse peri-implantation development and embryo dormancy
• Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage
• Pause and play: insights into mammalian embryonic diapause
• Defining the spatiotemporal expression pattern of Rap1 in the chicken embryonic spinal cord
• Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling

Discussions

• Kim, Y. S., Fan, R., Lith, S. C., Dicke, A. K., Drexler, H. C., Kremer, L., ... & Bedzhov, I. (2022). Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition. Developmenta [bsky, 3 points, 0 comments]