Differential effects of psilocybin and lisuride on serotonin and dopamine neuronal activity and behavior

2025/10/01 by Brandon Richardson, Antonio Inserra, Michael Pileggi +15 · 1 voice
Chemistry · Neuroscience · Psychology · #Chemical synthesis and alkaloids #Neurotransmitter Receptor Influence on Behavior #Psychedelics and Drug Studies

paper · doi:10.1016/j.pnpbp.2025.111522

crossref issued 2025/10/01 · crossref published 2025/10/01 · crossref published-print 2025/10/01 · openalex publication_date 2025/10/01 · crossref created 2025/10/10 · openalex created_date 2025/10/11 · crossref deposited 2025/11/04 · crossref indexed 2026/06/17 · openalex updated_date 2026/07/22

Citations

• Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
• Trial of Psilocybin versus Escitalopram for Depression
• Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression
• Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
• Psilocybin promotes neuroplasticity and induces rapid and sustained antidepressant-like effects in mice

Discussions

• Excited to share my new publication! 📄 We show how #psilocybin and #lisuride differ in their effects on #serotonin and #dopamine systems, shedding light on how #psychedelics act in the brain. doi. [bsky, 3 points, 0 comments]