Recounting the history of polyploid research in D. melanogaster : 1 century since 2 reports of 3 flies with 4 sets of chromosomes

2025/10/10 by Lewis I. Held · 1 voice
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Chromosomal and Genetic Variations #Evolution and Genetic Dynamics

paper · doi:10.1080/19336934.2025.2572865

openalex publication_date 2025/10/10 · openalex created_date 2025/10/11 · openalex updated_date 2026/07/15

Abstract

females - curiosities that had never been seen before. The authors, Calvin Bridges and Lilian Morgan, were among the famed founders of fly genetics in T.H. Morgan's lab at Columbia University. Sadly, their findings have faded into the fog of ancient fly lore. This review exhumes those relics in order to offer modern fly-pushers some possible avenues for polyploid research. That subfield is undergoing a revival that may interest them.

Citations

• Positional information and the spatial pattern of cellular differentiation
• Spermless males fail to remedy the low fecundity of parthenogenetic females in D. melanogaster
• Cold-induced meiotic nondisjunction in D. melanogaster

Discussions

• Marking the centenary of the first report of polyploidy in Drosophila, Lewis Held has authored a provocative review in Fly on the history and recent revival of research into the phenomenon - see doi.o [bsky, 3 points, 0 comments]

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