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One-Step Photoreduction of Nitroarenes to Nitrosoarenes

2026/06/25 by J P Keech, Narva Deshwar Kushwaha, James R. Bour · 1 voice
Chemistry · #Asymmetric Hydrogenation and Catalysis #Nanomaterials for catalytic reactions #Radical Photochemical Reactions

paper · pdf · doi:10.1021/acs.orglett.6c02016

openalex publication_date 2026/06/25 · openalex created_date 2026/06/26 · openalex updated_date 2026/07/27

Abstract

Nitrosoarenes are versatile synthons, but their selective synthesis from abundant feedstocks remains challenging because conventional methods often require harsh conditions that can result in over-reduction and over-oxidation. Here, we report a photomediated deoxygenation of nitroarenes to nitrosoarenes using electron-poor phosphines as oxygen atom acceptors. Careful selection of the oxygen atom acceptor enables selective arrest at the nitroso oxidation state, affording nitrosoarenes directly from nitroarenes in good yields under mild conditions.

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