Diagnostic Value of Procalcitonin for Bacterial Meningitis in Children: A Comparison Analysis Between Serum and Cerebrospinal Fluid Procalcitonin Levels

2018/10/29 by Li Zhang, Lan Ma, Xianghong Zhou +6

paper · doi:10.1177/0009922818809477

crossref issued 2018/10/29 · crossref published 2018/10/29 · crossref published-online 2018/10/29 · crossref created 2018/10/29 · crossref published-print 2019/02/01 · crossref deposited 2026/04/28 · crossref indexed 2026/07/29

Abstract

The aim of this study was to analyze and compare procalcitonin (PCT) levels in serum and cerebrospinal fluid (CSF) as tools for detecting bacterial meningitis (BM) in children. Serum and CSF PCT levels as well as albumin index (AI = CSF albumin/serum albumin × 1000) were measured from 29 BM, 25 viral meningitis (VM), and 47 non-meningitis patients. Differences between groups only for CSF PCT were significant. A stronger positive correlation between CSF PCT level and AI was observed in the BM patients ( R = 0.68, P

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