Emerging resistance mechanisms to newer β-lactams in Pseudomonas aeruginosa

2025/03/21 by Antonio Oliver, Jorge Arca-Suárez, María A. Gomis-Font +2 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #Antibiotics Pharmacokinetics and Efficacy #Infections and bacterial resistance

paper · doi:10.1016/j.cmi.2025.03.013

openalex publication_date 2025/03/21 · crossref created 2025/03/21 · openalex created_date 2025/10/10 · crossref issued 2025/11/01 · crossref published 2025/11/01 · crossref published-print 2025/11/01 · crossref deposited 2026/03/31 · openalex updated_date 2026/07/28 · crossref indexed 2026/07/28

Citations

• The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
• Antibacterial-ResistantPseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms
• AmpC β-Lactamases

Cited by

• Preventing resistance development in infections by OXA β-lactamase-producing Pseudomonas aeruginosa : correlating clinical outcomes with hollow-fibre model input
• Pa REx: an open-source pipeline for the automated analysis of Pseudomonas aeruginosa resistomes from whole-genome sequences
• Contribution of mutational resistance mechanisms and acquired β-lactamases to cefiderocol/xeruborbactam susceptibility in Pseudomonas aeruginosa

Discussions

• Emerging resistance mechanisms to newer β-lactams in Pseudomonas aeruginosa ➡️Mutations of AmpC, OXA-2/10, KPC, GES ➡️Efflux pumps ➡️PBP mutations ➡️Iron transport systems ➡️Others mutations: large g [bsky, 4 points, 0 comments]