Urogenital Schistosomiasis Mimicking IgG4-RD in a Patient With HIV

2025/03/18 by Guillemette Gagey, D. Sorial, Camille Rasmussen +7 · 1 voice
Medicine · Biochemistry, Genetics and Molecular Biology · #Pancreatitis Pathology and Treatment #Amyloidosis: Diagnosis, Treatment, Outcomes #Amoebic Infections and Treatments

paper · pdf · doi:10.1093/ofid/ofaf136

openalex publication_date 2025/03/18 · openalex created_date 2025/03/19 · openalex updated_date 2026/07/31

Abstract

This article reports a case of urogenital schistosomiasis mimicking IgG4-related disease (IgG4-RD) in a 47-year-old immunocompromised man with HIV. Initially diagnosed with IgG4-RD, further biopsies revealed schistosoma eggs. Elevated IgG4 levels indicated a Th2 immune response, highlighting its complex role in antischistosomal immunity and the need for careful differential diagnosis.

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