A mechanism for adaptive genome regulation in cancer

2026/04/15 by Gustavo S. França, Itai Yanai · 1 voice
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #FOXO transcription factor regulation #Melanoma and MAPK Pathways

paper · doi:10.1038/s41586-026-10269-1

crossref issued 2026/04/15 · crossref published 2026/04/15 · crossref published-online 2026/04/15 · openalex publication_date 2026/04/15 · crossref created 2026/04/15 · crossref deposited 2026/04/15 · crossref published-print 2026/04/16 · openalex created_date 2026/04/16 · openalex updated_date 2026/07/23 · crossref indexed 2026/07/31

Citations

• Genetic regulatory mechanisms in the synthesis of proteins
• AP-1 subunits: quarrel and harmony among siblings
• Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
• Defining trained immunity and its role in health and disease
• Metabolic reprogramming and cancer progression
• The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
• Dynamic regulation of tissue fluidity controls skin repair during wound healing

Discussions

• 🆕 research in Nature suggests cancer cells can learn to resist therapy, not by mutating, but by reprogramming themselves. In #lungcancer, resistance to targeted treatments is a big challenge. Unders [bsky, 4 points, 0 comments]