Synthetic autotrophic yeast enables high itaconic acid production from CO 2 via integrated pathway and process design

2025/01/01 by Özge Ata, Lisa Lutz, Michael Baumschabl +1 · 1 voice
Biochemistry, Genetics and Molecular Biology · Engineering · #Microbial Metabolic Engineering and Bioproduction #Microbial metabolism and enzyme function #Catalysis for Biomass Conversion

paper · pdf · doi:10.1039/d5gc03149d

openalex publication_date 2025/01/01 · openalex created_date 2025/09/27 · openalex updated_date 2026/07/28

Abstract

We show that combining pathway and process engineering enables synthetic autotrophic K. phaffii to produce ∼12 g L −1 itaconic acid from CO 2 , highlighting the role of interplay between native and heterologous metabolic pathways and process design.

Discussions

• Published in Green Chemistry doi.org/10.1039/D5GC... [bsky, 4 points, 0 comments]

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