Diagnostic yield of blood cultures in febrile neutropenia—a real-world observational study from an academic medical center during blood culture bottle shortage

2025/10/10 by Yuanli Lei, Maria Alkozah, Rita Wilson Dib +4 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Bacterial Identification and Susceptibility Testing #Neutropenia and Cancer Infections #Hematological disorders and diagnostics

paper · pdf · doi:10.1017/ice.2025.10310

openalex publication_date 2025/10/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/21

Abstract

This single-center retrospective analysis evaluated the yield of blood cultures in patients with febrile neutropenia during a supply shortage. The detection rate of true bacteremia was observed to increase with the number of sets obtained, although this increase was not statistically significant. Findings support limiting repeat cultures within 48 hours.

Discussions

• Out now in @ichejournal.bsky.social , with @ritawilson.bsky.social and others, our report on the blood culture bottle shortage last year affecting the diagnostic yield in febrile neutropenia @ou.edu [bsky, 4 points, 1 comments]

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