A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands

2024/12/10 by Kejia Li, Shijie Chen, Keyun Wang +18 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Biotin and Related Studies #Click Chemistry and Applications

paper · doi:10.1038/s41592-024-02553-7

crossref issued 2024/12/10 · crossref published 2024/12/10 · crossref published-online 2024/12/10 · openalex publication_date 2024/12/10 · crossref created 2024/12/10 · crossref published-print 2025/02/01 · openalex created_date 2025/10/10 · crossref deposited 2026/07/30 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31

Citations

• The InterPro protein families and domains database: 20 years on

Cited by

• In-source fragmentation in mass spectrometry-based proteomics: prevalence, impact, and strategies for mitigation

Discussions

• Insightful talk by Mingliang Ye at #ISCPDD. She talked about the use of #ChemicalProteomics for the study of target engagement in complex biological systems. Exciting insights into peptide-centric loc [bsky, 4 points, 0 comments]