2025/02/17 by Zeyuan Meng, Meng, Zeyuan, Lovely Yeswanth Panchumarthi +11 · 1 citation
Medicine · #ECG Monitoring and Analysis #FOS: Computer and information sciences #FOS: Electrical engineering #Machine Learning (cs.LG) #Signal Processing (eess.SP) #electronic engineering #information engineering
paper · pdf · doi:10.48550/arxiv.2502.17476
openalex publication_date 2025/02/17 · openalex created_date 2025/10/15 · openalex updated_date 2026/07/28
Acute Coronary Syndrome (ACS) is a life-threatening cardiovascular condition where early and accurate diagnosis is critical for effective treatment and improved patient outcomes. This study explores the use of ECG foundation models, specifically ST-MEM and ECG-FM, to enhance ACS risk assessment using prehospital ECG data collected in ambulances. Both models leverage self-supervised learning (SSL), with ST-MEM using a reconstruction-based approach and ECG-FM employing contrastive learning, capturing unique spatial and temporal ECG features. We evaluate the performance of these models individually and through a fusion approach, where their embeddings are combined for enhanced prediction. Results demonstrate that both foundation models outperform a baseline ResNet-50 model, with the fusion-based approach achieving the highest performance (AUROC: 0.843 +/- 0.006, AUCPR: 0.674 +/- 0.012). These findings highlight the potential of ECG foundation models for early ACS detection and motivate further exploration of advanced fusion strategies to maximize complementary feature utilization.