2017/09/09 by E. Moura, Enio Moura, Cláudia Turra Pimpão +1
Biochemistry, Genetics and Molecular Biology · #Cleft Lip and Palate Research #Craniofacial Disorders and Treatments #dental development and anomalies
paper · pdf · doi:10.1111/jsap.12730
crossref issued 2017/09/09 · crossref published 2017/09/09 · crossref published-online 2017/09/09 · openalex publication_date 2017/09/09 · crossref created 2017/09/09 · crossref published-print 2017/11/01 · crossref deposited 2024/06/26 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31
An easy-to-use classification that enables an accurate record of canine cleft lip and palate is fundamental for effective communication between professionals and researchers and optimal use of published information. Here we present how a classification system for human cleft lip and palate can be used to register spontaneous cases in dogs, highlighting its advantages. This system is based on four topographic areas with a numerical representation of the severity of the cleft in each area. The use of spontaneous cases has the advantage of providing clefts that are naturally similar to their human counterparts for surgical, genetic and genomic studies and, furthermore, will reduce the need for experimental models of this condition.