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The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue

2021/03/28 by Żaneta Ciosek, Karolina Kot, Danuta Kosik-Bogacka +2
Medicine · Nursing · #Magnesium in Health and Disease #Parathyroid Disorders and Treatments #Trace Elements in Health

paper · pdf · doi:10.3390/biom11040506

openalex publication_date 2021/03/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium-phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements that may act either indirectly through the regulation of macromineral metabolism, or directly by affecting osteoblast and osteoclast proliferation or activity, or through becoming part of the bone mineral matrix. This study analyzes the skeletal impact of macroelements (calcium, magnesium, phosphorus), microelements (fluorine), and heavy metals (lead), and discusses the concentration of each of these elements in the various bone tissues.

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