Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

2020/05/20 by Alba Grifoni, Daniela Weiskopf, Sydney I. Ramirez +20 · 18 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #COVID-19 Clinical Research Studies #SARS-CoV-2 and COVID-19 Research #vaccines and immunoinformatics approaches

paper · pdf · doi:10.1016/j.cell.2020.05.015

openalex publication_date 2020/05/20 · crossref created 2020/05/20 · openalex created_date 2020/05/21 · crossref issued 2020/06/01 · crossref published 2020/06/01 · crossref published-print 2020/06/01 · crossref deposited 2026/04/29 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31

Cited by

• SARS-CoV-2: The Interplay Between Evolution and Host Immunity
• Spatial instruction of tissue immunity
• Interactions between seasonal human coronaviruses and implications for the SARS-CoV-2 pandemic: A retrospective study in Stockholm, Sweden, 2009-2020
• T cells in health and disease
• Vaccines for COVID-19
• The SARS-CoV-2 spike protein is vulnerable to moderate electric fields
• SARS-CoV-2 spike-specific nasal-resident CD49a+CD8+ memory T cells exert immediate effector functions with enhanced IFN-γ production
• Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants
• The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination
• SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection
• Transforming vaccinology
• Visualizing the invisible: The effect of asymptomatic transmission on the outbreak dynamics of COVID-19
• Rare variable M. tuberculosis antigens induce predominant Th17 responses in human infection
• Pre-COVID-19 ex vivo cross-reactive IFN-γ cellular response to SARS-CoV-2 spike overlapping peptides is more prevalent among Kenyan compared to Swedish adults
• Development of SARS-CoV-2 as a viral vector: A novel intranasal bivalent vaccine for SARS-CoV-2 and RSV
• <i>In vivo</i> determination of protective antibody thresholds for SARS-CoV-2 variants using mouse models
• Immune landscape of COVID-19 recovery: Nucleocapsid as a major target of CD8+ T cell antiviral responses in convalescent HLA-A*02+ individuals from Brazil
• COVID-19 vaccine [wikipedia]