2020/01/01 by Ana I. Pérez-Jiménez, Danya Lyu, Zhixuan Lu +2 · 2 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Materials Science · #Biosensors and Analytical Detection #Gold and Silver Nanoparticles Synthesis and Applications #Spectroscopy Techniques in Biomedical and Chemical Research
paper · pdf · doi:10.1039/d0sc00809e
openalex publication_date 2020/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique with sensitivity down to the single molecule level that provides fine molecular fingerprints, allowing for direct identification of target analytes. Extensive theoretical and experimental research, together with continuous development of nanotechnology, has significantly broadened the scope of SERS and made it a hot research field in chemistry, physics, materials, biomedicine, and so on. However, SERS has not been developed into a routine analytical technique, and continuous efforts have been made to address the problems preventing its real-world application. The present minireview focuses on analyzing current and potential strategies to tackle problems and realize the SERS performance necessary for translation to practical applications.