Macrophage diversity in cancer revisited in the era of single-cell omics

2022/06/09 by Ruoyu Ma, Ruo-Yu Ma, Annabel Black +2 · 12 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Immune cells in cancer #Phagocytosis and Immune Regulation #Single-cell and spatial transcriptomics

paper · pdf · doi:10.1016/j.it.2022.04.008

openalex publication_date 2022/06/09 · crossref created 2022/06/09 · crossref issued 2022/07/01 · crossref published 2022/07/01 · crossref published-print 2022/07/01 · openalex created_date 2025/10/10 · crossref deposited 2025/10/26 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/30

Citations

• Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer
• Recepción del testimonio
• TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy
• A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells
• Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
• Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease
• Exploring tissue architecture using spatial transcriptomics
• Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level
• A single-cell and spatially resolved atlas of human breast cancers
• Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
• Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

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• Multicellular origins of murine ovarian inflammaging
• Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation
• STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma model
• Cancer-myeloid cell invasive program in pediatric-type diffuse high-grade glioma
• TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages
• Hardwired and rewired: Tissue macrophages in homeostasis and cancer
• The Role of Macrophages in Cancer: From Basic Research to Clinical Applications
• Histone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche
• Peritoneal resident macrophages constitute an immunosuppressive environment in peritoneal metastasized colorectal cancer
• Aberrant Activation of Wound-Healing Programs within the Metastatic Niche Facilitates Lung Colonization by Osteosarcoma Cells
• The role of tumor microenvironment and immune cell crosstalk in triple-negative breast cancer (TNBC): Emerging therapeutic opportunities